منابع مشابه
Utilization of ketone bodies by mammalian tissues.
It is now well established that ketone bodies (acetoacetate and D-3-hydroxybutyrate) are metabolized by many mammalian tissues and that the rate of utilization is mainly dependent on their availability in the circulation. The aim in this contribution is to summarize briefly the pathways of ketone-body metabolism and to discuss the role of ketone bodies m various tissues. For a detailed review o...
متن کاملHypoxia Induced Preferential Ketone Utilization by 319 Rat Brain Slices
When exposed to hypoxia, intact mice, with elevated blood ketones, live longer than mice with normal blood ketones. To evaluate a possible mechanism responsible for this phenomenon a rat brain slice preparation was used to determine if brain tissue would utilize glucose or ketones preferentially during exposure to reduced oxygen. Reducing available oxygen in the incubation medium from 95%, in s...
متن کاملHypoxia induced preferential ketone utilization by rat brain slices.
When exposed to hypoxia, intact mice, with elevated blood ketones, live longer than mice with normal blood ketones. To evaluate a possible mechanism responsible for this phenomenon a rat brain slice preparation was used to determine if brain tissue would utilize glucose or ketones preferentially during exposure to reduced oxygen. Reducing available oxygen in the incubation medium from 95%, in s...
متن کاملGlucagon stimulates ketone utilization by rat brain slices.
Glucagon has been shown previously to increase further the enhanced tolerance for hypoxia observed in mice with elevated blood ketones. Glucagon is also known to increase blood glucose and to alter directly the metabolism of some (liver) cells. Both the increase in blood glucose and altered cellular metabolism could contribute to the increase in tolerance for hypoxia observed in mice given gluc...
متن کاملHypoxia Induced Preferential Ketone Utilization by 319 Rat Brain Slices
When exposed to hypoxia, intact mice, with elevated blood ketones, live longer than mice with normal blood ketones. To evaluate a possible mechanism responsible for this phenomenon a rat brain slice preparation was used to determine if brain tissue would utilize glucose or ketones preferentially during exposure to reduced oxygen. Reducing available oxygen in the incubation medium from 95%, in s...
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ژورنال
عنوان ژورنال: The Journal of Pediatric Research
سال: 2015
ISSN: 2147-9445
DOI: 10.4274/jpr.85856